Is routine histological examination of gall bladder specimens justifiable?

نویسندگان

  • M I M De Zoysa
  • S K L A De Silva
  • A Illeperuma
چکیده

OBJECTIVE To assess the safety of confining histological examination to gall bladders with radiological and macroscopic features suggestive of cancer. DESIGN Retrospective study. Setting Department of Histopathology, National Hospital of Sri Lanka. METHOD Analysis of all cholecystectomies performed at a tertiary care hospital during a one year period. Computerised histopathological reports and case notes were studied. RESULTS Four hundred and seventy seven patients had undergone cholecystectomy for symptomatic gall stones. Four of these patients were found to have gall bladder cancer. In two of them the diagnosis had been suspected on pre-operative ultrasound scan. In the other two, gall bladder cancer was suspected at the time of surgery. Gall bladder cancer was found in 0.8% of specimens and it was suspected perioperatively in all these patients. CONCLUSION Our preliminary results suggest that a more selective approach to gall bladder histology may result in saving processing time and costs without adversely affecting patient safety.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathological examination of various lesions of gall bladder in routine 488 cholecystectomy specimens - A hospital based study

Disorders of gall bladder affect significant portion of population. Gall bladder is affected by inflammation, infection as well as benign and malignant conditions. Most (95%) of gall bladder diseases are attributable to cholelithiasis (stone) where females are affected more than male. Early diagnosis and treatment greatly reduce themortality and morbidity. The aim of this article is to know the...

متن کامل

International Journal of Biological & Medical Research SPECTRUM OF HISTOPATHOLOGICAL CHANGES IN CHOLECYSTITIS

gall bladder cholecystitis histopathological changes smooth muscle hypertrophy fibrosis carcinoma in situ Introduction: Diseases of the gallbladder form an important component and are in fact the bread and butter of routine surgical practice. Though traditionally considered to be a disease of middle aged obese females, the stereotype does not always apply to clinical cases as it can occur in bo...

متن کامل

Impact of routine histopathological examination of gall bladder specimens on early detection of malignancy - a study of 4,115 cholecystectomy specimens.

Gall bladder carcinoma is the most common cancer of biliary tree, characterized by rapid progression and a very high mortality rate. Detection at an early stage, however, is indicative of a very good prognosis and prolonged survival. The practice of histopathological examination of gall bladder specimens removed for clinically benign conditions and its usefulness has been a subject of controver...

متن کامل

Spontaneous Necrosis of the Gall Bladder.

RUPTURE of the gall bladder is not an uncommon phenomenon usually associated with gangrene following acute calculous cholecystitis. Cases have been reported following non-calculous cholecy-stitis (Maingot, 1957) and there are other isolated cases of rarer causes. Case Report A male, aged 58, presented with a history of bleeding per rectum for six months. Routine sig-moidoscopy showed a carcinom...

متن کامل

Practice of surgeons regarding examination of pathological specimens in operating room.

BACKGROUND The debate of routine versus selective submission of specimens for histopathology makes it important to know the present practice of surgeons. The objective of this study was to determine the proportion of general surgeons examining the gall bladder and appendix specimens in operating room before submission for histopathology. METHODS This questionnaire based survey was conducted f...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Ceylon medical journal

دوره 55 1  شماره 

صفحات  -

تاریخ انتشار 2010